Research &amp; Analysis

What Andrew Huberman Actually Says About Peptides

Huberman is the most quoted voice in peptides and the most selectively quoted. A faithful summary of his two Huberman Lab episodes: the mechanisms he finds credible, the compounds he tells listeners to avoid, and the sourcing advice that almost never survives the clip.

20 Aug 202611 min read

FDA Updates Its Framework for Generic Peptide Drugs: Why the 2026 Guidance Matters

On 28 July 2026 the FDA released 17 revised draft product-specific guidances for generic peptide drugs — and withdrew the 2021 synthetic peptide guidance that underpinned the field. Here is what changed on impurities, higher order structure and immunogenicity testing.

19 Aug 20268 min read

Research

Why Pharmaceutical Companies Are Spending Billions on Peptide Manufacturing

Samsung Biologics' $1.8B bid for PolyPeptide is the latest in a wave of peptide capacity deals. Inside the GLP-1 demand shock, SPPS economics, purification bottlenecks and why CDMO capacity became a strategic asset.

19 Aug 202611 min read

Avexitide Phase 3 Success Shows Peptide Therapeutics Extend Far Beyond Weight Loss

Amylyx's avexitide cut Level 2 and 3 hypoglycemic events by 55% in Phase 3. Why a GLP-1 receptor antagonist shows peptide therapeutics reach far past obesity drugs.

19 Aug 20267 min read

AI Could Dramatically Accelerate the Search for New Therapeutic Peptides

Peptide discovery is slow, expensive and multi-parameter. New AI platforms such as PeptiVerse predict solubility, toxicity, permeability and half-life before synthesis — but a prediction is still not evidence.

19 Aug 20268 min read

Peptide Hype vs Peptide Science: Why Preclinical Research Is Often Misunderstood

Stanford researchers say the peptide craze has outrun the evidence. A plain-English guide to in-vitro, animal and clinical research, why mouse studies rarely translate, and how to read the phrase 'shown to improve healing in studies'.

19 Aug 20269 min read

GLP-1 Peptides vs 'Classic' Research Peptides: Not the Same Category

Semaglutide, tirzepatide and retatrutide sit on an evidence base of tens of thousands of trial participants. BPC-157 and TB-500 have zero human trials. The market's confidence runs in the opposite direction to the data.

14 July 202611 min read

Ipamorelin vs CJC-1295 vs Sermorelin: What's Actually Different

They are not three versions of the same thing. Two act on one receptor, one acts on another — and the 'CJC-1295' you were sold might be one of two very different molecules.

14 July 202610 min read

BPC-157 vs TB-500: What the Evidence Actually Shows

Different mechanisms, overlapping claims, and a shared problem: neither has a single published human trial. Also, TB-500 is not Thymosin Beta-4, and the difference matters.

14 July 202611 min read

TB-500 (Thymosin Beta-4): Actin Regulation and Tissue Repair Research

TB-500 is a synthetic analogue of Thymosin Beta-4, a ubiquitous 43-amino acid peptide involved in actin sequestration, angiogenesis, and wound healing. This article reviews the research literature on its mechanisms and studied biological effects.

20 June 20269 min read

Melanotan I and Melanotan II: Melanocortin Receptor Research

Melanotan I and Melanotan II are synthetic alpha-MSH analogues studied for their effects on melanogenesis via melanocortin receptors. This article covers their structural differences, receptor selectivity, and the research literature.

10 June 202610 min read

CJC-1295 and Ipamorelin: Growth Hormone Axis Research

CJC-1295 is a long-acting GHRH analogue and ipamorelin is a selective ghrelin mimetic. Research on each compound and their studied effects on GH secretion profiles.

25 May 20268 min read

NAD+ in Cellular Energy and Ageing Research: What the Science Shows

Nicotinamide adenine dinucleotide (NAD+) is a central coenzyme in cellular metabolism. Research on NAD+ decline with age and its links to sirtuin activation has generated significant scientific interest.

8 May 20269 min read

Semax Research Overview: ACTH-Derived Nootropic Peptide

Semax is a synthetic heptapeptide derived from the ACTH(4-10) sequence, studied for neuroprotective effects, BDNF upregulation, and cognitive function in preclinical models.

22 Apr 20267 min read

GHK-Cu (Copper Peptide): Research Overview and Mechanisms

GHK-Cu is a naturally occurring copper-binding tripeptide studied for its roles in collagen synthesis, wound healing, and gene expression regulation. A review of published research.

10 Apr 20268 min read

BPC-157 Research Overview: What the Science Shows

A comprehensive review of preclinical BPC-157 research including its studied mechanisms, molecular structure, and key findings from published literature.

8 Jan 20269 min read

Retatrutide vs Tirzepatide vs Semaglutide: Research Comparison

A technical comparison of three GLP-1 receptor-targeting compounds: single, dual, and triple agonist mechanisms in preclinical and clinical research.

10 Dec 20258 min read

Legal & Compliance

Eli Lilly Targets Retatrutide Sellers as Scrutiny of the Peptide Market Intensifies

Eli Lilly filed six lawsuits on 12 August 2026 over alleged unauthorised retatrutide sales. What the investigational compound is, why the allegations remain unproven, and what the case signals for the wider peptide market.

19 Aug 20268 min read

FDA Peptide Review: What the BPC-157, TB-500 and MOTS-c Debate Actually Means

The FDA's July 2026 compounding advisory committee backed six of seven peptides against its own scientists' advice. What that vote means, what it does not mean, and what the FDA review documents actually found.

19 Aug 202611 min read

Peptides and Australian Customs: What Actually Happens at the Border

A straight answer on import law, what a seizure notice means, and whether 'research use only' labelling protects an individual importer. It does not.

14 July 20269 min read

Are Research Peptides Legal to Buy in Australia?

A clear explanation of the legal status of research peptides in Australia, including relevant legislation, permitted uses, and what buyers need to know.

20 Jan 20265 min read

Industry & Regulation

Hims & Hers Is Moving Into Peptides: What It Signals for the Industry

Hims & Hers plans to sell legally compoundable peptides by end-2026 and is testing BPC-157. What its pharmacy infrastructure, the FDA 503A vote and analyst caution mean for the peptide market.

19 Aug 20269 min read

Quality & Testing

How to Read a Peptide Certificate of Analysis (and Spot a Fake One)

Most buyers glance at the purity percentage and stop. That number is the least informative part of a CoA. Here is what each section actually tells you, and the forgery tells worth knowing.

14 July 202611 min read

Quality & Testing

How to Spot a Scam Peptide Supplier (and Why Prices Vary So Much)

The most common scam is not a fake product. It is a real product with less peptide in the vial than the label claims — and it is invisible without testing.

14 July 202610 min read

Quality & Testing

What is HPLC Purity and Why Does It Matter for Research Peptides?

HPLC (High-Performance Liquid Chromatography) is the gold standard for peptide purity verification. Learn what it measures, why 99%+ matters, and how to read a COA.

20 Dec 20256 min read

Research Guides

Peptide Concentration Math: mg, mcg, mL and Insulin Syringe Units

The arithmetic that connects a lyophilised vial to a volume measurement — including how to work out what is in a blended vial, and why blends constrain you.

14 July 20269 min read

Does Australian Heat Degrade Peptides in Transit?

Lyophilised peptides are far more heat-tolerant than the forums assume — and the real threats to your vial are condensation and freeze-thaw cycles, not a warm week in a mail bag.

14 July 20268 min read

Sterile Water vs Bacteriostatic Water: Does It Actually Matter?

Yes — and the difference determines whether your vial survives a second puncture. Also: why you reconstitute the whole vial rather than dosing from dry powder.

14 July 20267 min read

Peptide Storage Guide: How to Maximise Stability

Proper storage is critical to maintaining peptide integrity. Learn the correct temperature requirements and handling practices for lyophilised and reconstituted peptides.

28 Nov 20255 min read