Melanotan I 10mg
99.2% HPLC PurityA linear alpha-MSH analogue studied for its effect on melanin production.
A$69.99AUD
Melanotan II 10mg
SKU: PW-010 • Batch: PW-260309
99.1% HPLC PurityCOA Verified ✓
4.8 (5 reviews)
Cyclic alpha-MSH analogue studied in pigmentation and tanning research — the cyclised counterpart to Melanotan I. 99.1% HPLC purity, COA verified.
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Key Research Features
- 99.1% HPLC purity (independently verified)
- Cyclic α-MSH analogue, broad MC receptor profile
- Full COA documentation
- Manufactured in Australia
- Enzymatic degradation resistance vs linear analogues
- Batch PW-260309, COA available
Molecular Details
- Sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
- Molecular Formula
- C₅₀H₆₉N₁₅O₉
- CAS Number
- 121062-08-6
- Molecular Weight
- 1024.18 Da
- Purity
- 99.1%
- Form
- Lyophilised powder
- Appearance
- White/off-white lyophilised powder
Purity independently verified at a leading Australian university via HPLC & mass spectrometry.
Usage & Storage
- Quantity
- 10mg / vial
- Dosage Notes
- Research protocols vary. Published preclinical studies have explored subcutaneous administration at varying concentration ranges. Consult published literature for specific study designs.
- Reconstitution
- Reconstitute with 1–2mL bacteriostatic water. Swirl gently; do not shake. Allow to fully dissolve before use.
- Injection Route
- Subcutaneous (research protocols)
- Storage Temp
- −20°C for long-term storage
- Storage Conditions
- Store lyophilised at −20°C, protected from light. After reconstitution, refrigerate at 2–8°C and use within 4 weeks.
- Packaging
- Sterile, tamper-evident research vial
Description
Melanotan II is a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone (α-MSH). Its cyclic structure, formed by the D-Phe substitution and lactam bridge, confers increased receptor affinity and resistance to enzymatic degradation compared to the native hormone. Supplied at 99.1% HPLC purity with full COA.
Research has explored Melanotan II's activity at MC1R, MC3R, MC4R, and MC5R melanocortin receptor subtypes, producing a broader pharmacological profile than the linear Melanotan I (afamelanotide). Studies have investigated melanogenesis stimulation, pigmentation pathways, and receptor binding kinetics.
The cyclic structure is key to its pharmacological profile. Researchers should distinguish between MT-I (afamelanotide, linear) and MT-II (cyclic) when designing and interpreting research protocols.
Research & Guides
Frequently Asked Questions: Melanotan II
Melanotan II is a cyclic α-MSH analogue studied in preclinical research for effects on melanogenesis, pigmentation pathways, and MC receptor activity. For in-vitro laboratory research use only.
Our Melanotan II 10mg is independently verified at 99.1% HPLC purity with full COA documentation.
Store lyophilised at −20°C long term. Once reconstituted with BAC water, store at 2–8°C and use within 4 weeks, protected from light.
Melanotan II is legal to purchase in Australia for in-vitro research purposes. Not for human consumption, cosmetic, or therapeutic use.
Melanotan I is a linear α-MSH analogue with greater MC1R selectivity, while Melanotan II is cyclic with a broader melanocortin receptor binding profile including MC1R, MC3R, MC4R, and MC5R. They are structurally and pharmacologically distinct research compounds.
Research Use Only: Important Disclaimer
Melanotan II 10mg is sold strictly for in-vitro laboratory and research purposes only. This product is not intended for human consumption, therapeutic use, cosmetic use, or veterinary application. It has not been evaluated by the Therapeutic Goods Administration (TGA) or any other regulatory body for human use. You must be 18 years of age or older to purchase. By purchasing, you confirm that you are a qualified researcher and will use this product in compliance with all applicable Australian laws and regulations.
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